Cytogenetics Amniotic Fluid Chromosome Analysis
88235; 88269; 88280; 88285
Amniotic fluid chromosome analysis is recommended to be offered to all pregnant women by The American College of Obstetricians and Gynecologists (ACOG) for diagnostic testing (as opposed to just screening) for chromosome abnormalities Additional specific indications cytogenetic analysis include: abnormal maternal serum screening results, abnormalities seen on ultrasound, family history of a chromosome abnormality, or known parental balanced chromosome rearrangement.
Determine fetal karyotype.
15-20 mitotic spreads counted from separate in situ colonies and 2 banded karyotypes prepared
20-30 mL (15-20 mL for early amniocentesis)
Two 15 mL sterile orange-top tubes
Discard first 2 mL; then 15-25 mL amniotic fluid (less if early amniocentesis)
Please call our Client Services Department prior to sending first specimen. If additional testing such as DNA is indicated, call Client Services for further specimen requirements.
Causes for Rejection
Frozen specimen; hemolysis; quantity not sufficient for analysis; improper container; unlabeled or mislabeled specimen)
Maintain specimen at room temperature. Do not freeze.