Cytogenetics Blood Chromosome Analysis
88230; 88262; 88291
Indications for cytogenetic analysis on blood include: dysmorphic features, failure to thrive, developmental delay and/or intellectual disability; infertility and multiple pregnancy loss; and family history of chromosome abnormality, ultrasound abnormalities for (PUBS) or family history of chromosome abnormality.
Evaluate congenital malformations, intellectual disability, growth restriction, infertility, cryptorchidism, hypogonadism, amenorrhea (primary), abnormal/ambiguous genitalia, recurrent miscarriage, Turner syndrome, Klinefelter syndrome, Down syndrome, or other suspected chromosomal disorders.
Karyotype; Routine G-Banding;
5-10 mL (adult); 2-5 mL (child - less for newborn)
Green-top (sodium heparin) tube
High concentrations of heparin are toxic. Do not collect small volumes in large vacutainers or add additional heparin to specimens.
Causes for Rejection
Hemolysis; specimen clotted; use of improper anticoagulant; frozen specimen
Maintain specimen at room temperature. Do not freeze.