LabCorp and its Specialty Testing Group, a fully integrated portfolio of specialty and esoteric testing laboratories.

FirstScreen® – First Trimester Screening

CPT:

84163; 84702


Special Instructions

Integrated Genetics will only accept NT measurements from sonographers who have been certified by the Fetal Medicine Foundation (FMF) or the Nuchal Translucency Quality Review Program (NTQR). Please submit certification information before sending specimens for FirstScreen. Please contact our Client Services Department with any questions.



Specimen Requirements


Specimen

Whole blood, serum, or dried blood spot


Volume

Blood: 7-10 mL; Serum: 2-3 mL (unhemolyzed); Dried blood spot: minimum 3 circles


Container

Blood: Serum separator tube (SST) or red-top tube; Serum: Serum separator tube (SST); Dried blood spot: IG-Provided blood spot card


Collection

Blood: Allow to clot; centrifuge (15 minutes at 1000 g) to prevent hemolysis. Dried blood spot: If prenatal carrier screening for cystic fibrosis is ordered in conjunction with first trimester screening, all 6 circles should be filled.


Test Details


Use

FirstScreen screens for fetal Down syndrome and trisomy 18 between 10 weeks/3 days and 13 weeks/6 days (10.4-13.9 weeks, CRL = 38-84 mm). Two biochemical markers, pregnancy associated plasma protein (PAPP-A) and human chorionic gonadotropin (hCG), and the nuchal translucency (NT) ultrasound measurement are combined to provide a risk assessment in the first trimester.


Pregnancy Week

0–13 Weeks

Patient?

Patient?

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