Maternal Cell Contamination Analysis (In-House Samples Only)
A maternal blood sample is required to rule out the presence of maternal cells in prenatal samples of uncultured amniotic fluid, CVS, or CVS cultures.
Whole blood or mouthwash (see specimen kit for detailed instructions)
Adults: 10 mL whole blood or mouthwash.
Lavender-top (EDTA) tube or yellow-top (ACD-A) tube or mouthwash kit
Mouthwash collection: Patient should not eat, drink, smoke or chew gum for at least one hour prior to collection. (See specimen kit for detailed instructions).
Mouthwash samples can be sent when ordering up to two tests. When ordering more than two tests, blood samples are required. 10 mL of Scope® mouthwash that has been swished vigorously for at least 1 minute. Collect in orange-top 50 mL polypropylene tube.
Maintain specimen at room temperature
Causes for Rejection
Frozen specimen; hemolysis; quantity not sufficient for analysis; improper container; unlabeled or mislabeled specimen
False positive or false negative results may occur for reasons that include: genetic variants, technical handling, blood transfusions, bone marrow transplantation, mislabeling of samples, or erroneous representation of family relationships
Analysis of short tandem repeat markers by polymerase chain reaction (PCR) and capillary electrophoresis