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Maternal Cell Contamination Analysis (In-House Samples Only)



Special Instructions

A maternal blood sample is required to rule out the presence of maternal cells in prenatal samples of uncultured amniotic fluid, CVS, or CVS cultures.

Specimen Requirements


Whole blood or mouthwash (see specimen kit for detailed instructions)


Adults: 10 mL whole blood or mouthwash.


Lavender-top (EDTA) tube or yellow-top (ACD-A) tube or mouthwash kit


Mouthwash collection:  Patient should not eat, drink, smoke or chew gum for at least one hour prior to collection. (See specimen kit for detailed instructions). 

Mouthwash samples can be sent when ordering up to two tests. When ordering more than two tests, blood samples are required.  10 mL of Scope® mouthwash that has been swished vigorously for at least 1 minute. Collect in orange-top 50 mL polypropylene tube. 

Storage Instructions

Maintain specimen at room temperature

Causes for Rejection

Frozen specimen; hemolysis; quantity not sufficient for analysis; improper container; unlabeled or mislabeled specimen


Test Details


False positive or false negative results may occur for reasons that include: genetic variants, technical handling, blood transfusions, bone marrow transplantation, mislabeling of samples, or erroneous representation of family relationships


Analysis of short tandem repeat markers by polymerase chain reaction (PCR) and capillary electrophoresis

Pregnancy Week

0–13 Weeks
14–21 Weeks
22+ Weeks



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