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SequentialScreen Part 2


82105; 84702; 82677; 86336

Special Instructions

Integrated Genetics will only accept NT measurements from sonographers who have been certified by the Fetal Medicine Foundation (FMF) or the Nuchal Translucency Quality Review Program (NTQR). Please submit certification information before sending specimens for SequentialScreen. Please contact our Client Services Department with any questions.

Specimen Requirements


Whole blood, serum, or dried blood spot


2-3 mL serum (unhemolyzed); Fill a minimum of three circles completely with blood; 7 mL blood


Serum separator tube (SST); IG provided filter paper/test requisition; blood in Serum separator tube (SST) or red-top tube


Avoid hemolysis. Send complete specimen in the original tube. Do not pour off.

Storage Instructions

Store at room temperature.

Causes for Rejection

Gross hemolysis; gross lipemia; quantity not sufficient for analysis; improper specimen type

Test Details


Screening test for open neural tube defects, Down syndrome, and trisomy 18


SequentialScreen requires two specimens: one collected in the first trimester and one in the second trimester. This test number is for the first trimester portion of the test. Result interpretation for the first trimester portion will be provided only for screen-positive specimens. Result interpretation for all others will be provided only when the second trimester specimen is received and tested. This is a screening test. A positive result means that diagnostic testing may be offered to the pregnant woman to determine if a neural tube defect or chromosome abnormality is present.

Pregnancy Week

0–13 Weeks
14–21 Weeks



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