LabCorp and its Specialty Testing Group, a fully integrated portfolio of specialty and esoteric testing laboratories.

Noninvasive prenatal testing

Different NIPTs for different patient needs

No other genetic testing laboratory currently offers as much expertise, experience, and choice in NIPT—noninvasive prenatal testing, also called NIPS or cfDNA (cell-free DNA) screening.

With the 2016 acquisition of Sequenom, creator of the first commercially available NIPT, Integrated Genetics now offers three NIPTs—with more than 1 million tests run in total.

Each NIPT offers different capabilities and/or panels to suit the specific needs of your patients and your practice.

MaterniT GENOME

MaterniT® GENOME

The only clinically validated genome-wide NIPT, screens all 23 chromosome pairs, reporting aneuploidies, large deletions and duplications greater than 7 Mb in addition to select microdeletions; after more than 35,000 tests resulted, more than 29% of all positive findings were only detectable using genome-wide cfDNA, the methodology used by MaterniT GENOME, as compared to traditional NIPT.1

MaterniT 21 PLUS

MaterniT® 21 PLUS

The pioneering NIPT with more than 750,000 tests run; screens the core trisomies 21, 18, and 13, and (optionally) fetal sex, clinically relevant microdeletions, sex chromosome aneuploidies, and trisomies 16 and 22.

InformaSeq

informaSeq®

Integrated Genetics’ legacy NIPT; an ideal fit for physicians who want to only test for trisomies 21, 18, and 13, and optional testing for fetal sex, monosomy X, triple X, Klinefelter syndrome, and XXY, or Jacobs syndrome.

MaterniT® GENOME MaterniT® 21 PLUS informaSeq®
Detects trisomy 21 (Down syndrome)
Detects trisomy 21 (Down syndrome)
Detects trisomy 18 (Edwards syndrome)
Detects trisomy 18 (Edwards syndrome)
Detects trisomy 13 (Patau syndrome)
Detects trisomy 13 (Patau syndrome)
Detects sex chromosome abnormalities*
Detects sex chromosome abnormalities*
Reports fetal fraction
Reports fetal fraction
Reports fetal sex*
Reports fetal sex*
Multiple gestations†
Multiple gestations†
Detects additional trisomies 22, 16*
Detects additional trisomies 22, 16*
Detects select microdeletions, such as 22q11.2 (DiGeorge syndrome)**
Detects select microdeletions, such as 22q11.2 (DiGeorge syndrome)**
Performed as early as 9 weeks
Performed as early as 9 weeks
~5 calendar day turnaround time
~5 calendar day turnaround time
Genome-wide analysis of all chromosomes
Genome-wide analysis of all chromosomes
Reports on any trisomy or monosomy
Reports on any trisomy or monosomy
Detects subchromosomal abnormalities ≥ 7 Mb
Detects subchromosomal abnormalities ≥ 7 Mb
Learn more Learn more Learn more

MaterniT 21 PLUS, MaterniT GENOME, and informaSeq are laboratory-developed test developed and performed exclusively by Integrated Genetics. 

* Optional reporting     † informaSeq is validated for singleton and twin pregnancies     ** Optional reporting for MaterniT 21 PLUS

Do you have patients who have not had a test and have questions about costs or coverage? Send them to our estimator.

Do you have patients who have already had a test performed and are wondering when their results will be in? We can help.

Patients with questions about their test results who need schedule an appointment with a counselor can do so online.

References

  1. Ehrich M, Tynan J, Mazloom A, Almasri E, McCullough R, Boomer T, et al. Genome-wide cfDNA screening: clinical laboratory experience with the first 10,000 cases. Genet Med. 2017 Jun 15. 1-6.